Moderna submits application to US regulator for Covid booster shot

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AFP

Washington (AFP) – Moderna on Wednesday announced it had begun submitting an application to the US Food and Drug Administration to authorize a booster of its Covid vaccine after trial data showed a significant increase in antibodies against variants. The third shot of the vaccine, known as mRNA-1273, was given to 344 participants in a study six months after their second dose. The first two doses were 100 micrograms, while the booster was half that at 50 micrograms.  An analysis showed the booster increased neutralizing antibody levels against variants of concern, including Delta by more than 4…

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